Keep a list of all of the items you utilize (which include prescription/nonprescription medicine and herbal solutions) and share it with your health care provider and pharmacist. Do not commence, stop, or change the dosage of any medicines with out your health practitioner's acceptance.
The respiratory depression includes a reduction while in the responsiveness of your Mind stem respiratory centers to the two will increase in carbon dioxide pressure also to electrical stimulation.
Children 12 to eighteen yrs of age—Use and dose must be determined by your medical doctor. Kids youthful than twelve decades of age—Really should not be used in these patients. Missed Dose Should you overlook a dose of the medicine, skip the missed dose and return to your normal dosing timetable. Never double doses.
Promethazine and codeine mix is used To alleviate cough, runny or stuffy nose, sneezing, or other symptoms due to allergies or even the common cold.
A Unique MedGuide will probably be supplied for you via the pharmacist with Just about every prescription and refill. You should definitely read through this info very carefully each time.
However it can help Many of us, this medication incorporates a possibility for abuse and will sometimes trigger habit. This danger may very well be bigger In case you have a substance use dysfunction (which include overuse of or habit to medicines/Liquor).
Consequences on the Cardiovascular Technique Codeine makes peripheral vasodilation which can bring about orthostatic hypotension or syncope. Manifestations of histamine launch and/or peripheral vasodilation might include things like pruritus, flushing, purple eyes and perspiring and/or orthostatic hypotension.
If the response to an opioid antagonist is suboptimal or only quick in nature, administer added antagonist as directed with the products’s prescribing info. The respiratory depressant effects of promethazine aren't reversed by opioid antagonists, like naloxone.
The lowest helpful dosage should be utilized, and also other drugs that influence respiration really should be prevented. Get health-related assist immediately from the not likely occasion that slow/shallow respiratory takes place. Promethazine shouldn't be used by children with liver condition (together with doable Reyes syndrome).
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Mainly because opioid agonists may perhaps raise biliary tract force, with resultant increase in plasma amylase or lipase concentrations, determination of those enzyme ranges may very well be unreliable for twenty-four several hours immediately after administration of the dose of Promethazine HCl and Codeine Phosphate Oral Alternative.
Tend not to flush remedies down the bathroom or pour them into a drain Unless of course instructed to take action. Adequately discard this product or service when it can be expired or no longer required. Speak to your pharmacist or community waste disposal firm.
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The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals less than six several years of age, mainly because The mix might cause deadly respiratory despair During this age inhabitants. It's important that promethazine with codeine syrup is measured with an exact measuring gadget (see Safety measures-Information For Clients).